(A) Assessment of rearing of Wistar rats in the control (saline) and drug (pramipexole) groups in the Open Field. * indicates a significant decrease in rearing in the drug group compared to the baseline level from days 1 to 43 of treatment (ANOVA, p<0.05); @ indicates a significant decrease in rearing in the control group relative to baseline from days 15 to 29 of the treatment (ANOVA, p<0.05); # indicates a same day difference between the groups on day 1 of treatment (ANOVA, p<0.05). B assessment of grooming (time, seconds) in the Open Field in the control (saline) and drug (pramipexole) groups. * indicates a significant decrease in grooming in the drug group compared to baseline from days 1 to 71 of treatment (ANOVA, p<0.05); @ indicates a significant decrease in grooming in the control group relative to baseline from days 1 to 8 and days 22 to 71 of treatment (ANOVA, p<0.05); # indicates a same day difference between the groups on day 15 of treatment (ANOVA, p<0.05).