TABLE 3.

Subset of genes conserved between both microarray data sets

Full gene name	Gene symbol	Functional relationship to treatment	Fold change (antagonist/agonist)
Serpin peptidase inhibitor, clade A, member 3	SERPINA3	Known downstream target of MR in cardiac cells (25)	−2.2
FBJ murine osteosarcoma viral oncogene homolog	FOS	Up-regulated by aldosterone and GR-overexpression (25, 50)	−2.6
Growth arrest and DNA-damage-inducible, β	GADD45B	Up-regulated in stressful growth conditions (52)	−2.2
Ankyrin repeat domain 1	ANKRD1	Transcript levels altered in numerous muscle diseases (36)	−2.2
Natriuretic peptide receptor C/guanylate cyclase C	NPR3	Involved in MR-regulated pathways (46)	−2.5

These gene changes are likely caused directly by MR modulation; gene function or regulation related to treatment is listed.