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. 2015 Jul 29;29(11):4713–4725. doi: 10.1096/fj.15-272443

Figure 2.

Figure 2.

A) Systolic and diastolic BP was elevated in CBS+/− mice. After 2 wk of 5-Aza treatment, both decreased toward normal levels. Baseline BP was recorded before starting 5-Aza or saline treatment and continued later at weekly intervals. B) Doppler waveform of the intrarenal cortical artery from all groups. C) PSV and RI in the cortical artery were increased in CBS+/− mice. Both these indices were reduced after 5-Aza treatment. Data are the means ± sem (n = 7/group). *P < 0.05 vs. CBS+/− with saline; †P < 0.05 vs. WT groups.