Table 1.
Results of two-way ANOVA on the effects of Na2SeO3 (Se), VOSO4 (V), and the interactive effects between Na2SeO3 and VOSO4 (V × Se) on CHO-K1 cell damage measured with a resazurin assay
| Two-way anova analysis | Character of interaction | |
|---|---|---|
| Main effect of V | F = 448.948, p = 0.000 | – |
| Main effect of Se (0.1 μM) | NS | – |
| Interactive effect of V × Se (0.1 μM) | NS | – |
| Main effect of V | F = 728.505, p = 0.000 | – |
| Main effect of Se (0.5 μM) | NS | – |
| Interactive effect of V × Se (0.5 μM) | F = 4.777, p = 0.034 | Synergistica |
| Main effect of V | F = 1110.036, p = 0.000 | – |
| Main effect of Se (1.0 μM) | F = 8.249, p = 0.006 | – |
| Interactive effect of V × Se (1.0 μM) | F = 10.578, p = 0.002 | Synergistica |
NS no significant effect
aThe effect of V in the presence of Se (V + Se effect) > sum of the effects of V and Se alone (Se effect + V effect) (synergistic interaction)