Table 2.
Variable | Class | Total population | Company workers | Farmers | ||||||
---|---|---|---|---|---|---|---|---|---|---|
N | Mean (SD) or n (%)a | p | N | Mean (SD) or n (%)a | p | N | Mean (SD) or n (%)a | p | ||
Age (years) | LTF | 124 | 41.85 (12.5) | 0.88 | 109 | 41.55 (12.4) | 0.24 | 15 | 44.03 (13.5) | 0.63 |
FU | 259 | 41.68 (9.8) | 179 | 40.02 (9.6) | 80 | 45.39 (9.2) | ||||
Femaleb | LTF | 124 | 17 (13.7) | 0.55 | 109 | 13 (11.9) | 0.41 | 15 | 4 (26.7) | 0.41 |
FU | 259 | 30 (11.6) | 179 | 16 (8.9) | 80 | 14 (17.5) | ||||
BMI (kg m−2) | LTF | 124 | 26.13 (4.3) | 0.90 | 109 | 26.14 (4.2) | 0.42 | 15 | 26.05 (4.9) | 0.37 |
FU | 259 | 26.08 (3.6) | 179 | 26.52 (3.6) | 80 | 25.10 (3.5) | ||||
Current smokerb | LTF | 124 | 41 (33.1) | 0.10 | 109 | 40 (36.7) | 0.15 | 15 | 1 (6.7) | 0.31 |
FU | 259 | 65 (25.1) | 179 | 51 (28.5) | 80 | 14 (17.5) | ||||
Farm childhoodb | LTF | 124 | 36 (29.0) | <0.01 | 109 | 25 (22.9) | <0.01 | 15 | 11 (73.3) | 0.28 |
FU | 259 | 148 (57.1) | 179 | 80 (44.7) | 80 | 68 (85.0) | ||||
Endotoxin exposurec (EU m−2) | LTF | 124 | 339.00 (6.4) | 0.79 | 109 | 376.77 (7.0) | 0.96 | 15 | 157.34 (1.8) | 0.22 |
FU | 259 | 322.36 (5.0) | 179 | 381.34 (5.9) | 80 | 221.34 (2.8) | ||||
Asthmab | LTF | 124 | 10 (8.1) | 0.89 | 109 | 7 (6.4) | 0.54 | 15 | 3 (20.0) | 0.21 |
FU | 259 | 22 (8.5) | 179 | 15 (8.4) | 80 | 7 (8.8) | ||||
Wheezeb | LTF | 124 | 18 (14.5) | 0.42 | 109 | 14 (12.8) | 0.67 | 15 | 4 (26.7) | 0.17 |
FU | 259 | 30 (11.6) | 179 | 20 (11.2) | 80 | 10 (12.5) | ||||
Lung function (% pred.) | ||||||||||
FEV1 | LTF | 124 | 106.05 (14.1) | 0.90 | 109 | 105.30 (14.0) | 0.46 | 15 | 111.49 (14.2) | 0.15 |
FU | 259 | 106.24 (15.0) | 179 | 106.61 (15.1) | 80 | 105.41 (15.0) | ||||
PEF | LTF | 124 | 113.60 (22.1) | 0.03 | 109 | 114.10 (22.7) | 0.04 | 15 | 109.96 (18.1) | 0.21 |
FU | 259 | 118.38 (19.3) | 179 | 119.31 (20.0) | 80 | 116.29 (17.6) | ||||
FVC | LTF | 124 | 112.22 (13.4) | 0.58 | 109 | 111.19 (12.9) | 0.89 | 15 | 119.72 (15.3) | 0.07 |
FU | 259 | 111.39 (13.9) | 179 | 110.96 (14.0) | 80 | 112.36 (13.9) | ||||
FEcNO (ppb) | LTF | 123 | 16.20 (1.9) | 0.13 | 108 | 15.71 (1.9) | 0.06 | 15 | 20.25 (1.9) | 0.44 |
FU | 258 | 18.07 (1.9) | 178 | 18.29 (1.9) | 80 | 17.58 (1.9) | ||||
Allergyb | LTF | 124 | 33 (26.6) | 0.81 | 109 | 27 (24.8) | 0.72 | 15 | 6 (40.0) | 0.51 |
FU | 259 | 66 (25.5) | 179 | 41 (22.9) | 80 | 25 (31.3) | ||||
Hay feverb | LTF | 124 | 20 (16.1) | 0.22 | 109 | 15 (13.8) | 0.34 | 15 | 5 (33.3) | 0.10 |
FU | 259 | 30 (11.6) | 179 | 18 (10.1) | 80 | 12 (15.0) | ||||
TotIgEc (IU/ml) | LTF | 117 | 24.35 (9.2) | 0.72 | 102 | 23.06 (9.4) | 0.61 | 15 | 35.31 (7.7) | 0.55 |
FU | 251 | 26.43 (7.3) | 175 | 26.45 (8.3) | 76 | 26.38 (5.4) | ||||
Atopyb | LTF | 117 | 22 (18.8) | 0.50 | 102 | 19 (18.6) | 0.35 | 15 | 3 (20.0) | 0.89 |
FU | 251 | 55 (21.9) | 175 | 41 (23.4) | 76 | 14 (18.4) | ||||
HDM spec. IgEb | LTF | 117 | 11 (9.4) | 0.30 | 102 | 8 (7.8) | 0.18 | 15 | 3 (20.0) | 0.49 |
FU | 251 | 33 (13.1) | 175 | 23 (13.1) | 76 | 10 (13.2) | ||||
Grass pollen spec. IgEb | LTF | 117 | 17 (14.5) | 0.49 | 102 | 15 (14.7) | 0.92 | 15 | 2 (13.3) | 0.38 |
FU | 251 | 30 (12.0) | 175 | 25 (14.3) | 76 | 5 (6.6) |
LTF lost to follow-up, FU included in follow-up
aMean (SD) for continuous variables and n (%) for categorical variables
bCategorical variable
cGeometric mean and SD