Skip to main content
. Author manuscript; available in PMC: 2015 Oct 17.
Published in final edited form as: J Thromb Thrombolysis. 2007 Feb 10;24(2):115–122. doi: 10.1007/s11239-007-0010-3

Fig. 4.

Fig. 4

Net t-PA release over the coronary bed was inhibited by the ADP P2Y1 receptor blocker MRS2179: t-PA was simultaneously measured in the coronary sinus (venous) and the femoral artery (arterial) before, during and after 10 min of coronary ischemia. The difference of measured levels of arterial and venous t-PA yielded a significantly decreased release of t-PA during the greater part of the ischemic period and the early phase of reperfusion by coronary infusion of MRS2179 during the first and tenth minute of coronary ischemia (2.5 ml of MRS2179, 10−3 M). n = 7–8, *p < 0.05