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. 2015 Oct 17;34:123. doi: 10.1186/s13046-015-0241-7

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© Ferrari et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Representative IFN-gamma cytokine release after stimulation of T-lymphocytes exposed to solitomab vs control BiTE®. A significant increase in IFN-gamma stained cells was consistently detected in both CD8⁺ or CD4⁺ T cells (CD8/INF-gamma, CTRL VS BITE, p = 0.001478197; CD4/INF-gamma, CTRL VS BITE, p = 7.84945E-06; CD8/IL4, CTRL VS BITE, p not significant; CD4/IL4, CTRL VS BITE p not significant)