Table 1. Anti-Toxoplasma Activity of Propranolol in Mice Peritoneal Exudates (Pre-Treatment Group).
| Drug/Dose, mg | Tachyzoites No. (× 104) | % Growth Inhibition a |
|---|---|---|
| Propranolol | ||
| 2 | 3771.6 ± 233.4 b | 37 |
| 3 | 3661.6 ± 622.3 | 39 |
| Propranolol and Pyrimethamine | ||
| 2 + 50 | 871.0 ± 486.9 b | 86 |
| 3 + 50 | 144.5 ± 84.1 b | 98 |
| Pyrimethamine, Pos. control | ||
| 50 | 3532 ± 38.8 | 41 |
| PBS, Neg. control | ||
| - | 5973.3 ± 388.8 | - |
a % Growth Inhibition = (1- No. of tachyzoites after treatment /No. of tachyzoites in negative control) × 100.
b Indicates a statistically significant difference compared to positive controls (P < 0.05).