Table 2. Anti-Toxoplasma Activity of Propranolol in Mice Peritoneal Exudates (Post-Treatment Group).
| Drug/Dose, mg | Tachyzoites No. (× 104) | % Growth Inhibition a |
|---|---|---|
| Propranolol | ||
| 2 | 1526.6 ± 171.4 b | 75 |
| 3 | 2948.3 ± 1452.8 b | 51 |
| Propranolol and Pyrimethamine | ||
| 2 + 50 | 2 ± 1 b | 99.9 |
| 3 + 50 | 6.6 ± 2.0 | 99.9 |
| Pyrimethamine (Pos. control) | ||
| 50 | 8 ± 2 | 99.9 |
| PBS (Neg. control) | ||
| - | 5990.0 ± 312.2 | - |
a % Growth Inhibition = (1- No. of tachyzoites after treatment /No. of tachyzoites in negative control) × 100.
b Indicates a statistically significant difference compared to positive controls (P < 0.05).