Table 1.
Patient characteristics at baseline categorized by the presence or absence of AKI
| Variables | Total | No AKI | AKI | P |
|---|---|---|---|---|
| Mean ± SD | (n = 121) | (n = 86) | (n = 35) | |
| Age (years) | 57.3 ± 14.7 | 56.4 ± 14.7 | 59.6 ± 14.8 | 0.27 |
| % Male | 75 (62 %) | 52 (60.5 %) | 23 (65.7 %) | 0.59 |
| Cause of cirrhosis | 0.74 | |||
| -Chronic hepatitis B/C | 63 (52.1 %) | 44 (51.2 %) | 19 (54.3 %) | |
| -Alcohol | 32 (26.4 %) | 25 (29.1 %) | 7 (20.0 %) | |
| -NASH | 7 (5.8 %) | 4 (4.7 %) | 3 (8.6 %) | |
| -Cryptogenic | 14 (11.6 %) | 9 (10.5 %) | 5 (14.3 %) | |
| -Autoimmune | 5 (4.1 %) | 4 (4.7 %) | 1 (2.9 %) | |
| Child-Pugh | 0.20 | |||
| A | 25 (20.7 %) | 21 (24.4 %) | 4 (11.4 %) | |
| B | 55 (45.5 %) | 39 (45.3 %) | 16 (45.7 %) | |
| C | 41 (33.9 %) | 26 (30.2 %) | 15 (42.9 %) | |
| Ascites | 68 (56.2 %) | 43 (50.0 %) | 25 (71.4 %) | 0.03 |
| MELD score | 14.9 ± 5.7 | 14.3 ± 5.9 | 16.4 ± 5.1 | 0.08 |
| Serum creatinine | 0.88 ± 0.29 | 0.83 ± 0.29 | 0.96 ± 0.28 | 0.05 |
| TB (mg/dl) | 4.7 ± 5.1 | 4.5 ± 4.4 | 5.2 ± 6.6 | 0.49 |
| DB (mg/dl) | 3.4 ± 4.3 | 3.2 ± 3.5 | 4.1 ± 5.8 | 0.28 |
| AST (U/L) | 139.7 ± 250.3 | 129.9 ± 259.8 | 163.7 ± 22 | 0.50 |
| - Median (IQR) | 73 (43.5–127) | 69.5 (44–119) | 82 (35–185) | |
| ALT (U/L) | 78.4 ± 174.5 | 72.6 ± 168.2 | 92.9 ± 190.38 | 0.56 |
| - Median (IQR) | 34 (24–53) | 33.5 (24–52) | (25–59) | |
| ALP (U/L) | 163 ± 108 | 143 ± 89 | 213 ± 134 | 0.001 |
| INR | 1.51 ± 0.77 | 1.51 ± 0.87 | 1.53 ± 0.45 | 0.93 |
| Albumin (g/dl) | 2.85 ± 0.86 | 2.9 ± 0.9 | 2.7 ± 0.6 | 0.23 |
| Hemoglobin (g/dl) | 10.7 ± 2.4 | 10.7 ± 2.2 | 10.6 ± 2.9 | 0.87 |
| WBC count (103/uL) | 9.86 ± 6.2 | 9.6 ± 6.1 | 10.4 ± 6.6 | 0.53 |
| Platelet (/103uL) | 128 ± 121 | 111 ± 64 | 170 ± 197 | 0.014 |