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. 2015 Aug 12;34(20):2522–2536. doi: 10.15252/embj.201490583

Figure 4.

Figure 4

Notch signaling regulates antral epithelial cell differentiation
  • A–O Analysis of surface mucous cells (A–E), deep mucous cells (F-J) or endocrine cells (K-O) by immunohistochemical analysis of antral paraffin sections and qRT–PCR analysis of antral RNA in control, DBZ and Lgr5; ROSANICD 4 weeks post-TX (mean ± SEM;n = 3–18 mice). *P < 0.05, **P < 0.01, ***P < 0.001 versus control using one-way ANOVA. Scale bars: 50 μm.
  • P–S Analysis of endocrine and deep mucous cell lineages in control (n = 16), DAPT-treated (n = 8) and Lgr5; ROSANICD (n = 8) antral organoids (mean ± SEM). *P < 0.05, **P < 0.01, ****P < 0.0001 versus control using one-way ANOVA.