Table 1.

Hemodynamic parameters following cocaine and cocaethylene with treatment from ILE

Cocaine					Cocaethylene
	RPP	dp/dt	−dp/dt	Line-P		RPP	dp/dt
10μM	79 ±5	85 ±4	85 ±5	107 ±3	10μM	84 ±5	90 ±5
+ILE	90 ±2	92 ±3	93 ±3	106 ±5	0.1% EtOH	96 ±2*	99 ±4
30μM	58 ±2	67 ±3	66 ±3	130 ±6	+ILE	101 ±3§	103 ±4*
+ILE	78 ±5 §	83 ±5¶	85 ±6¶	139 ±17	30μM	69 ±4	77 ±3
50μM	51 ±4	59 ±3	59 ±3	162 ±12	0.3% EtOH	82 ±2*	94 ±5§
+ILE	73 ±4¶	80 ±6¶	82 ±7†	170 ±26	+ILE	94 ±4	100 ±5¶
100μM	35 ±5	48 ±4	47 ±4	186 ±20	50μM	59 ±5	68 ±4
+ILE	56 ±3¶	64 ±8¶	67 ±8¶	198 ±31	0.5% EtOH	79 ±2¶	85 ±1¶
					+ILE	84 ±3§	95 ±5†

Values plotted as mean ± standard error (SEM)

RPP = rate pressure product; Line-P = line pressure; ILE = 0.25% infusion of lipid emulsion; EtOH = ethanol; dp/dt =

Difference from analogous treatment condition with cocaine or cocaethylene alone italicized

^*<0.05

^§<0.01

^¶<0.001

^†<0.0001