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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Mol Imaging Biol. 2015 Dec;17(6):848–855. doi: 10.1007/s11307-015-0858-0

Fig. 6.

Fig. 6

a PET coronal and axial images (left) and corresponding CT images (right) of a mouse injected with [18F]PARPi-FL (200 μCi in 100 μl 15 % PEG300/85 % 0.9 % saline); b PET coronal and axial images (left) and corresponding CT images (right) after pre-injection of blocking agent; c ex vivo blood half-life of [18F]PARPi-FL (n =4). Blood was collected at different time points (5, 15, 30, 60, and 120 min), weighed, and γ-counted. Results expressed as percent injected activity/gram (%IA/g); d biodistribution study in selected tissues. After injection of [18F]PARPi-FL into tumor xenograft mice, mice were euthanized and the radioactivity in the organs was counted (n =4); e selected tumor to non-target tissues ratio of [18F]PARPi-FL. Radioactivity in tissues is expressed as percent injected dose/gram. Error bars indicate standard deviation (n =4).