Table 2.
Median (interquartile range – IQR) arsenic concentrations (µg/L) and percent arsenic metabolites during pregnancy by HEV seroconversion status.
| HEV seroconverter |
pa | Non- seroconverter |
pa | pb | |
|---|---|---|---|---|---|
| Arsenobetaine (µg/L) | |||||
| 1st TM | 1.2 (0.8, 1.8) | 1.5 (1.0, 2.5) | 0.26 | ||
| 3rd TM | 0.6 (0.4, 1.1) | 0.01 | 0.7 (0.5, 1.1) | < 0.001 | 0.82 |
| ∑As (µg/L) | |||||
| 1st TM | 65.6 (40.8, 132.8) | 61.6 (37.0, 82.2) | 1.00 | ||
| 3rd TM | 64.7 (26.2, 105.9) | 1.00 | 35.9 (25.6, 77.4) | 0.002 | 0.03 |
| % DMA | |||||
| 1st TM | 76.7 (74.3, 80.5) | 80.3 (75.6, 82.9) | 0.003 | ||
| 3rd TM | 84.3 (80.4, 87.3) | < 0.001 | 84.8 (78.6, 88.1) | 0.003 | 0.50 |
| % MMA | |||||
| 1st TM | 7.6 (5.8, 9.6) | 6.7 (4.7, 8.7) | 0.50 | ||
| 3rd TM | 4.8 (4.1, 7.0) | 0.01 | 5.0 (3.7, 6.3) | 0.03 | 0.82 |
| % As(V) + As(III) | |||||
| 1st TM | 14.7 (12, 18) | 13.1 (11, 17) | 0.12 | ||
| 3rd TM | 10.2 (7.9, 13) | 0.001 | 9.9 (7.4, 13) | 0.07 | 0.37 |
| Total As (µg/L) | |||||
| 1st TM | 75.8 (41.3, 136.0) | 63.6 (44.6, 85.9) | 0.50 | ||
| 3rd TM | 66.4 (27.9, 119.2) | 0.82 | 37.7 (27.4, 79.5) | 0.007 | 0.03 |
Note. TM = trimester. PP = postpartum. ∑As = inorganic arsenic plus methylated species. As = arsenic. DMA = dimethylarsinic acid. MMA = methylarsonic acid.
p derived from Fisher's exact test of the equality of medians comparing 1st and 3rd TM.
p derived from Fisher's exact test of the equality of medians comparing HEV seroconverters to non-seroconverters.