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. 2015 Oct 4;2015:607120. doi: 10.1155/2015/607120

Figure 8.

Figure 8

Effect of EC specific overexpression of Scarb1 on atherosclerosis. Percent of aortic lesions, as determined by en face analysis, is shown (a) for Tie2-Scarb1 transgenic females (N = 9) versus C57Bl/6N control females (N = 14) on HFHC diet for 6 months (∗ P < 0.02), (b) for 8-month-old Tie2-Scarb1 × ApoE-KO mice (N = 22) versus nontransgenic sibling controls (N = 25) on normal chow diet (∗∗ P < 0.002), and (c) for Tie2-Scarb1 × Scarb1-KO mice (N = 12) versus nontransgenic sibling Scarb1-KO controls (N = 10) on HFHC diet for 3 months (P > 0.3).