Table 2.
Results of simple regression models among the 71 patients with early RA with the concentration of Lp-PLA2 at T0 as the dependent variable.
| Lp-PLA2 at T0 | |||
|---|---|---|---|
| β | 95% CI | p value | |
| IMT T0 (n = 70) | 9.7/mm | 2.1; 17.2 | 0.013† |
| IMT T5 (n = 70) | 8.8/mm | 1.4; 16.2 | 0.02† |
| FMD T0 (n = 70) | −2.4/% | −4.5; −0.4 | 0.02 |
| FMD T5 (n = 70) | −2.5/% | −4.6; −0.5 | 0.02 |
| Non-HDL-cholesterol T0 (n = 54) | 16.9/mmolL−1 | 5.8; 28.0 | 0.004 |
| HDL T0 (n = 55) | −22.6/mmolL−1 | −42.0; −3.1 | 0.02 |
| Diastolic blood pressure T0 (n = 66) | 1.3/mmHg | 0.1; 2.5 | 0.04 |
| Ever smoking (n = 70) | 0.8/year | 0.08; 1.4 | 0.03 |
| SCORE T0 (n = 53) | 11.4/unit | 3.3; 19.5 | 0.007 |
| Reynolds Risk Score T0 (n = 38) | 5.2/unit | 1.5; 8.8 | 0.007 |
| Larsen score T0 (n = 50) | 2.9/unit | 0.013; 5.90 | 0.05 |
†Still significant after adjustment for sex and age.
RA: rheumatoid arthritis; Lp-PLA2: lipoprotein-associated phospholipase A2; IMT: intima media thickness; FMD: flow mediated dilation; HDL: high-density lipoproteins.