(a).

Features	Ascending Colon
	Control	PSC	PSC + UC	PSC versus control	PSC + UC versus control	PSC versus PSC + UC
Architectural change	0.1 ± 0.1	0.4 ± 0.2	0.7 ± 0.2	NS	p = 0.015	NS
Chronic inflammatory infiltrate	0.4 ± 0.1	1.1 ± 0.2	1.5 ± 0.3	p = 0.01	p = 0.0003	NS
Lamina propria neutrophils and eosinophils	0.1 ± 0.1	0.5 ± 0.2	1.3 ± 0.3	NS	p = 0.001	p = 0.038
Neutrophils in epithelium	0.0	0.1 ± 0.1	0.3 ± 0.2	NS	NS	NS
Crypt destruction	0.0	0.0	0.5 ± 0.4	NS	NS	NS
Erosion or ulceration	0.0	0.4 ± 0.4	0.3 ± 0.3	NS	NS	NS
Total	0.5 ± 0.2	2.1 ± 0.4	3.6 ± 0.8	p  = 0.025	p  < 0.0001	p  = 0.038