(b).
Feature | Sigmoid colon | |||||
---|---|---|---|---|---|---|
Control | PSC | PSC + UC | PSC versus control | PSC + UC versus control | PSC versus PSC + UC | |
Architectural change | 0.1 ± 0.1 | 0.2 ± 0.2 | 0.9 ± 0.3 | NS | p = 0.0015 | p = 0.01 |
Chronic inflammatory infiltrate | 0.4 ± 0.1 | 0.4 ± 0.2 | 1.3 ± 0.1 | NS | p < 0.0001 | p = 0.0003 |
Lamina propria neutrophils and eosinophils | 0.0 | 0.1 ± 0.1 | 0.9 ± 0.2 | NS | p < 0.0001 | p = 0.0001 |
Neutrophils in epithelium | 0.0 | 0.0 | 0.1 ± 0.1 | NS | NS | NS |
Crypt destruction | 0.0 | 0.0 | 0.5 ± 0.4 | NS | NS (p = 0.054) | NS |
Erosion or ulceration | 0.0 | 0.0 | 0.4 ± 0.3 | NS | NS | NS |
Total | 0.5 ± 0.2 | 0.6 ± 0.3 | 2.9 ± 0.4 | NS | p < 0.0001 | p < 0.0001 |