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. 2015 Oct 17;15:128. doi: 10.1186/s12903-015-0105-8

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© Zhang et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — PAR-1 (a), PAR-2 (b) and PAR-3 (c) gene expression in response to P. gingivalis supernatant. PARs gene expression was evaluated by quantitative real-time RT-PCR (QRT-PCR) in response to cell-free supernatant from P. gingivalis and TLCK-preincubated supernatant in GECs. After P. gingivalis supernatant treatment, the expression of PAR-2 was upregulated compared to untreated control cells. Conversely, PAR-1 and PAR-3 expression was significantly downregulated. Data are shown as the mean with the standard deviation (mean ± SD). *, P < 0.05, compared with control values. Control: without supernatant stimulation. P. gingivalis S: P. gingivalis supernatant