Table 4.
Autoimmune conditions previously reported in persons with hemochromatosis1.
| Condition | Reference |
|---|---|
| Autoimmune hemolytic anemia | [14] |
| Celiac disease | [17, 19, 26–29] |
| Diabetes mellitus type 12 | [30] |
| Hashimoto's thyroiditis | [16, 31, 32] |
| Hyperthyroidism or Graves' disease | [16, 33–35] |
| Immune thrombocytopenia | [34] |
| Myasthenia gravis3 | [36] |
| Pernicious anemia | [37, 38] |
| Psoriasis | [39] |
| Rheumatoid arthritis | [40, 41] |
| Sarcoidosis4 | [18, 42] |
| Schnitzler's syndrome | [43] |
| Sclerosing cholangitis5 | [44] |
| Ulcerative colitis5 | [44] |
| Vitiligo | [15] |
1Hemochromatosis was defined as an adult-onset condition typical of HFE hemochromatosis in European white adults characterized by iron phenotyping, HLA typing or haplotyping, or HFE C282Y homozygosity. One HFE C282Y homozygote had collagenous sprue, a rare condition of uncertain etiology [45].
2Autoimmunity was not mentioned in descriptions of study subjects.
3This man had pure red cell aplasia of undefined cause.
4The case of a woman with sarcoidosis included herein was reported previously [18].
5Ulcerative colitis and sclerosing cholangitis occurred in the same man.