Figure 1.
5-HT-immunoreactive (IR) nerve fibers in the intermediate zone in the sacrocaudal spinal cord on the injured and uninjured side in different animal groups. (a–d) Photomicrographs of 5-HT-IR fibers in 5-day untreated group (a) and 5-HTP plus carbidopa treated group (b) and in 60-day untreated group (c) and 5-HTP plus carbidopa treated group (d). Dashed line represents the midline in each horizontal section. CC: central canal. Arrows in (b) and (d) indicate 5-HT-immunoreactive cells. Scale bar in (a), 100 μm. (e) Quantitative data of the density of 5-HT-IR fibers in different animals groups. ∗ P < 0.05, ∗∗ P < 0.01.