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Low concentration of SB203580 abolished the PEDF-induced p38/MAPK phosphorylation. Representative blots and data summary of phospho-p38 (p-p38) and p38 in HUVECs under PEDF (200 ng/mL), SB203580 (5 μmol/mL), and PEDF (200 ng/mL) + SB203580 (5/10/15 μmol/mL) treatment at 6 h. Representative western blots are shown. Graph represents the mean ± SD (n = 3 in each group) of the relative integrated signals. * P < 0.05, ** P < 0.01.
