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. Author manuscript; available in PMC: 2016 Oct 19.
Published in final edited form as: Angew Chem Int Ed Engl. 2015 Jun 26;54(43):12584–12587. doi: 10.1002/anie.201502494

Scheme 1.

Scheme 1

Methylerythritol phosphate (MEP) pathway. DXS: 1-deoxy-D-xylulose 5-phosphate synthase; DXR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; GcpE: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate reductase; LytB: 4-hydroxy-3-methylbut-2-enyl 1-phosphate reductase.