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. Author manuscript; available in PMC: 2015 Oct 18.
Published in final edited form as: Annu Rev Biophys. 2014;43:19–39. doi: 10.1146/annurev-biophys-051013-022754

Figure 5.

Figure 5

Landscape reconstruction from force-jump measurements. (a) Upon a decrease of the force to near zero (blue), the extension of a polyubiquitin molecule (black) decreases as it folds. Different folding curves at 10 pN show folding over different times (inset). (b) Extension distribution of the nonequilibrium trajectories from Equation 4. (c) Free-energy profile from Equation 5. Reprinted with permission from Reference 77. Copyright 2013 by the American Physics Society. Available online at http://link.aps.org/abstract/PRL/v110/e128301.