Table 1.
Nr. of cases |
Antibody |
||||||
---|---|---|---|---|---|---|---|
Examined block | Subregions | Her | Co | Tau | pTDP-43 | α-Syn | Aβ |
Frontal | Cortex | 18 | 10 | + | + | + | + |
White matter | 18 | 10 | + | + | + | + | |
Temporal | Cortex | 26 | 9 | + | + | + | + |
White matter | 26 | 9 | + | + | + | + | |
Occipital | Cortex | 17 | 6 | + | − | − | + |
White matter | 17 | 6 | + | − | − | + | |
Hippocampus + | CA4 | 26 | 11 | + | + | + | + |
CA2/3 | 26 | 11 | + | + | + | + | |
CA1 | 26 | 11 | + | + | + | + | |
Dentate gyrus | 26 | 11 | + | + | + | + | |
Subiculum | 26 | 11 | + | + | + | + | |
Entorhinal cortex | 26 | 11 | + | + | + | + | |
Fusiform Gyrus | 26 | 11 | + | + | + | + | |
White matter | 26 | 11 | + | + | + | + | |
Basal ganglia | Caudate nucleus | 24 | 10 | + | + | + | + |
Putamen | 24 | 10 | + | + | + | + | |
Accumbens nucleus | 24 | 10 | + | + | + | + | |
Globus pallidus | 24 | 10 | + | + | + | + | |
Thalamus | Dorsomedial nucleus | 20 | 11 | + | + | + | + |
Amygdala | Amygdala | 17 | 7 | + | + | + | + |
Basal nucleus | Basal nucleus | 17 | 7 | + | + | + | + |
Cerebellum | Purkinje cells | 2 | 2 | + | − | − | + |
Granular layer | 2 | 2 | + | − | − | + | |
Molecular layer | 2 | 2 | + | − | − | + | |
White matter | 2 | 2 | + | − | − | + | |
Dentate nucleus | 2 | 2 | + | − | − | + | |
Mesencephalon | Substantia nigra | 17 | 9 | + | + | + | + |
Ventral tegmental area | 17 | 9 | + | + | + | + | |
Dorsal raphe nucleus | 17 | 9 | + | + | + | + | |
Pons | Locus coeruleus | 4 | 2 | + | + | + | + |
Pontine base nuclei | 4 | 2 | + | + | + | + | |
Medulla oblongata | Inferior olives | 3 | 2 | + | + | + | + |
Dorsal vagus nucleus | 3 | 2 | + | + | + | + | |
Medullary raphe nuclei | 3 | 2 | + | + | + | + |