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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Neurobiol Aging. 2015 Aug 15;36(11):2946–2953. doi: 10.1016/j.neurobiolaging.2015.08.008

Figure 1.

Figure 1

illustrates representative CAA localization by the APOE genotypes. (A) shows a subject with ε3/3 genotype with sparse CAA which is confined to segmental deposition of β amyloid in only meningeal vessels, and the cortex has few β amyloid plaques. (B) shows a ε2 carrier with CAA present in meningeal and intracerebral cortical vessels, as well as few β amyloid plaques in the cortex. (C) shows a ε4 carrier with marked CAA in meningeal and intracerebral cortical vessels, as well as frequent β amyloid plaques in the cortex. Scale bar = 150 μm.