Table 1.
Descriptive of the study group (N=1,062)
| Age at death (mean, SD) | 88.7, 6.6 |
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| |
| Female Sex (N, %) | 687, 64.7% |
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| |
| Education (mean, SD) | 16.3, 3.6 |
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| |
| Non-Hispanic Whites (N, %) | 1014, 95.6% |
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| |
| APOE genotypes (N, %) | |
| ε2/2 | 7, 0.7% |
| ε2/3 | 134, 12.6% |
| ε2/4 | 21, 2.0% |
| ε3/3 | 644, 60.6% |
| ε3/4 | 240, 22.6% |
| ε4/4 | 16, 1.5% |
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| |
| Composite measure of AD pathology (mean, SD)1 | 0.76, 0.40 |
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| |
| Pathologic diagnosis of AD by NIA-Reagan criteria (N, %) | 672, 63.3% |
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| |
| Macroscopic infarcts (N, %) | 368, 34.7% |
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| |
| Microinfarcts (N, %) | 304, 28.6% |
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| |
| Lewy Bodies (N, %) | 229, 21.6% |
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| |
| Rating of CAA (N, %) | |
| None | 220, 20.7% |
| Mild | 468, 44.1% |
| Moderate | 245, 23.1% |
| Severe | 129, 12.1% |
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| |
| Capillary CAA (N, %) | 170, 16.0% |
1
Square root transformed