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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Neurobiol Aging. 2015 Aug 15;36(11):2946–2953. doi: 10.1016/j.neurobiolaging.2015.08.008

Table 3.

Association of APOE with capillary CAA

Model 1
OR (95% CI)		 Model 2
OR (95% CI)		 Model 3
OR (95% CI)
Male Sex 0.902 (0.616, 1.320) 0.989 (0.670, 1.459) 0.986 (0.667, 1.460)
Education 1.045 (0.994, 1.098) 1.055 (1.003, 1.110)* 1.057 (1.004, 1.113)*
AD1 - 3.797 (2.247, 6.418)* 3.816 (2.243, 6.494)*
Macroscopic infarcts - - 0.936 (0.637, 1.375)
Microinfarcts - - 1.534 (1.037, 2.270)*
Lewy Bodies - - 1.374 (0.913, 2.067)
APOE ε2 0.966 (0.569, 1.640) 1.250 (0.723, 2.161) 1.269 (0.731, 2.203)
APOE ε4 5.747 (4.018, 8.221)* 4.155 (2.845, 6.066)* 4.149 (2.835, 6.073)*
1

Composite measure of AD pathology;

*

p<0.05;

Model 1 is adjusted for demographics; Model 2 adjusted for demographics and AD pathology; Model 3 is adjusted for demographics, AD pathology, as well as presence of infarcts and Lewy bodies;