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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Neurobiol Aging. 2015 Aug 15;36(11):2946–2953. doi: 10.1016/j.neurobiolaging.2015.08.008

Table 4.

Association of APOE with CAA by capillary involvement

Without capillaries
OR (95% CI)		 With capillaries
OR (95% CI)
Age at death 1.028 (1.008, 1.049)* 1.007 (0.951, 1.065)
Male Sex 1.225 (0.936, 1.604) 1.005 (0.523, 1.932)
Education 0.995 (0.961, 1.031) 0.967 (0.891, 1.049)
AD1 5.594 (3.881, 8.061)* 1.494 (0.571, 3.910)
Macroscopic infarcts 0.924 (0.703, 1.215) 1.149 (0.611, 2.159)
Microinfarcts 1.133 (0.851, 1.511) 0.896 (0.476, 1.683)
Lewy Bodies 0.843 (0.617, 1.153) 0.947 (0.494, 1.815)
APOE ε2 1.566 (1.103, 2.223)* 4.221 (1.487, 11.982)*
APOE ε4 1.636 (1.179, 2.269)* 1.640 (0.863, 3.115)
1

Composite measure of AD pathology;

*

p<0.05.

Both models were adjusted for demographics, AD pathology, as well as presence of infarcts and Lewy bodies;