Skip to main content
. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Transl Res. 2015 Jun 10;166(5):485–501. doi: 10.1016/j.trsl.2015.06.004

Figure 7. N-Mgb+SnPP (Rx) treatment confers protection against unilateral ischemia-reperfusion (I/R)- induced progressive kidney disease.

Figure 7

Mice were subjected to 30 min of left renal ischemia with or without N-Mgb-SnPP pre-treatment 18 hrs earlier. At 2 weeks post ischemia, I/R led to a 38% reduction in renal mass (gauged by kidney weight). Pre-treatment (Rx) conferred significant protection, as gauged by only a 12% reduction in renal mass. Protection was also implied by marked reductions in NGAL mRNA and protein levels in the 2 week post ischemic left kidneys.