Skip to main content
. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neuropsychologia. 2015 Jul 18;77:19–34. doi: 10.1016/j.neuropsychologia.2015.07.019

Table 2. Regions associated with Switching.

Condition x y z mm3
Switching > Rule Application (29 voxels / 232 mm3)
 R. Middle Frontal Gyrus 52 40 14 785
 R. Medial Parietal / Posterior Cingulate 29 -57 7 5045
 L. Medial Parietal / Posterior Cingulate -19 -59 22 2555
 L. Parahippocampal Gyrus -22 -49 -6 1557
 L. Ventral Putamen -19 9 -8 1878
Conjunction (25 voxels / 200 mm3.)
 L. Ventral Putamen -16 9 -9 723

 Switching > Hypothesis Testing (36 voxels / 288 mm3)
 R Medial Frontal Gyrus 8 15 52 13662
 L. Medial Frontal Gyrus -8 6 59 15417
 R. Middle Frontal Gyrus 60 11 35 2646
 L. Precentral Gyrus -47 2 54 19440
 L. Precentral Gyrus -63 -2 45 12582
 R. Postcentral Gyrus 70 -13 54 297
 R. Precuneus 24 -67 30 20088
 R. Precuneus 28 -53 48 5292
 L. Precuneus -27 -67 34 4833
 L. Inferior Frontal Gyrus -50 10 30 14472
 R. Inferior Frontal Gyrus 33 42 -12 8208
 R. Inferior Frontal Gyrus 30 36 -34 2025
 L. Inferior Frontal Gyrus -32 39 -37 2700
 R. Inferior Frontal Gyrus 27 35 -14 3645
 L. Insula -41 17 6 2133
 R. Cerebellum 43 -46 -23 7074
 L. Fusiform Gyrus -47 -58 -10 837
 R. Cuneus 37 -86 34 14067
 R. Lingual Gyrus 27 -62 9 13824

 L. Hippocampus -24 -40 4 4779
 R. Ventral Putamen and Caudate 20 19 -9 23247
 R. Caudate Head 14 20 8 10152
 L. Ventral Putamen -15 4 -4 15579
 Hypothesis Testing > Switching
 L. Middle Frontal Gyrus -44 53 -18 20655
 L. Superior Frontal Gyrus -14 44 49 3699
 R. Superior Frontal Gyrus 30 70 19 243
 L. Inferior Frontal Gyrus -41 41 -10 9963
 R. Middle Temporal Gyrus 69 -2 -34 2106
 R. Superior Temporal Gyrus 69 20 -30 7047
 R. Fusiform Gyrus 59 -46 -26 2160
 B. Cerebellum 1 -95 -21 2403
 L. Cerebellum -54 -75 -25 2295
 L. Parahippocampal Gyrus -31 -28 -34 2916
 L. Caudate Body -18 3 27 4050
 R. Caudate Tail 24 -26 19 540

Feature cued + Externally cued > Feedback cued (threshold: 15 voxels / 120 mm3)
 R. Fusiform Gyrus 55 -60 -20 593
 R. Occipital Lobe 23 -89 -20 2142
 R. Fusiform Gyrus 36 -66 -19 548
 R. Fusiform Gyrus 35 -41 -25 525
 L. Inferior Temporal Gyrus, Occipital Lobe -55 -59 -8 10764
 R. Supplementary Motor Area 21 18 60 5248
 L. Middle Frontal Gyrus -33 58 4 1679
 L. Premotor Cortex -34 2 63 678
 L. Middle Frontal Gyrus -49 40 16 3794
 L Supplementary Motor Area -22 21 57 3776
 R. Caudate / Putamen 10 9 -2 739
 L. Caudate / Putamen -3 7 5 2371
Externally cued > Feature cued (threshold: 28 voxels / 224 mm3)
 R. Parahippocampal Gyrus 20 -46 -4 2528
 L. Parahippocampal Gyrus 0 -59 -6 3216
 B. Occipital Lobe 17 -95 18 2939
 L. Lateral Occipital Lobe -39 -90 5 3534
 R Middle Temporal Gyrus 71 -3 -2 1105
 R. Medial Frontal / Supplementary Motor area 14 -20 61 815
 B. Medial Parietal / Precuneus -9 -49 64 5229

Note: All contrasts were individually corrected for multple comparisons using the cluster level threshold simulator, voxelwise threshold p < .005, alpha = .05. The resulting cluster threshold for each contrast is indicated in parenthesis next to the contrast name. The conjunction analysis was a conjunction of three contrasts: feedback cued > rule application, feature cued > rule application, and externally cued > rule application. x, y, z: MNI coordinates. mm3: Size of cluster in cubic millimeters.