Table 1.
REGARDS (2003–2007) cohort characteristics and biomarker measurements by Oxidative Balance Score categories
| Covariates | Equal-interval OBS categories | |||||
|---|---|---|---|---|---|---|
| 3–7 (n=861) |
8–12 (n=6,050) |
13–17 (n=8,862) |
18–21 (n=3,682) |
22–26 (n=370) |
P- value |
|
| Age (yrs.), Mean (SD) | 61 (8.9) | 64 (9.2) | 65 (9.2) | 66 (9.1) | 67 (8.6) | <0.01 |
| Male, (%) | 416 (48.3) | 2,789 (46.1) | 3,901 (44.0) | 1,581 (42.9) | 142 (38.4) | <0.01 |
| Caucasian, (%) | 555 (64.5) | 3937 (65.1) | 5,957 (67.2) | 2,543 (69.8) | 271 (73.2) | <0.01 |
| Education, (%) | <0.01 | |||||
| College education or higher | 212 (24.6) | 1,942 (32.1) | 3,489 (39.4) | 1,647 (44.7) | 178 (48.1) | |
| Some college | 269 (31.2) | 1,682 (27.8) | 2,402 (27.1) | 989 (26.9) | 92 (24.9) | |
| High school graduate | 275 (31.9) | 1,731 (28.6) | 2,187 (24.7) | 787 (21.4) | 82 (22.2) | |
| Less than high school | 105 (12.3) | 695 (11.5) | 784 (8.8) | 259 (7.0) | 18 (4.8) | |
| Geographical region, (%) | <0.01 | |||||
| Stroke Belt | 327 (38.0) | 2,187 (36.2) | 3,014 (34.0) | 1,199 (32.6) | 125 (33.8) | |
| Stroke Buckle | 181 (21.0) | 1,413 (23.4) | 1,921 (21.7) | 763 (20.7) | 68 (18.4) | |
| Other | 3,353 (41.0) | 2,450 (40.4) | 3,927 (44.3) | 1,720 (46.7) | 177 (47.8) | |
| Exercise, (%) | <0.01 | |||||
| ≥4 times/week | 206 (23.9) | 1,655 (27.4) | 2,780 (31.4) | 1,299 (35.3) | 131 (35.4) | |
| 1–3 times/week | 301 (35.0) | 2,150 (35.5) | 3,390 (38.3) | 1,365 (37.1) | 133 (36.0) | |
| None | 354 (41.1) | 2,245 (37.1) | 2,692 (30.3) | 1,018 (27.6) | 106 (28.6) | |
| Total energy intake (kcal/day), Mean (SD) | 1,444 (560) | 1,508 (624) | 1,751 (705) | 1,977 (768) | 1,915 (644) | <0.01 |
| BMI (kg/m2), Mean (SD) | 28.1 (5.5) | 29.2 (6.0) | 29.2 (5.9) | 29.3 (6.0) | 29.4 (6.4) | <0.01 |
Population: any participant with at least one biomarker (n=19,825).
Analysis for biomarker limited to participants on whom the biomarker was measured: CRP, n=19,531; total cholesterol, n=19,790; HDL, n=19,685; LDL, n=19,416; triglycerides, n=19,782; albumin, n=14,475; WBC count, n=13,716.
Values presented as mean (SD) or number (%).