Table 4.

Associations between the Oxidative Balance Score and serum HDL-cholesterol level^a by sex in the REGARDS cohort

Sex	LS Mean (SD)	Normal HDL	Low HDL	OR (95% CI)d	p-trende
Femaleb
OBS Interval
3–7	55.49 (0.75)	380	62	1.0	0.05
8–12	57.12 (0.29)	2,872	364	0.71 (0.53 – 0.95)
13–17	57.57 (0.24)	4,376	538	0.72 (0.54 – 0.96)
18–21	57.59 (0.36)	1,862	214	0.68 (0.50 – 0.93)
22–26	57.54 (1.04)	209	19	0.48 (0.28 – 0.83)
Malec
OBS Interval
3–7	47.06 (0.64)	277	136	1.0	0.13
8–12	45.99 (0.27)	1,725	1,050	1.22 (0.97 – 1.53)
13–17	45.65 (0.24)	2,420	1,464	1.25 (1.00 – 1.56)
18–21	45.56 (0.36)	997	579	1.22 (0.96 – 1.55)
22–26	45.10 (1.09)	83	58	1.63 (1.09 – 2.45)

^aNormal HDL (≥40 mg/dL); Low HDL (<40 mg/dL)

^bNormal HDL (n=9,699); Low HDL (n=1,197)

^cNormal HDL (n=5,502); Low HDL (n=3,287)

^dAdjusted for age, race, BMI, total daily energy, education, region, and exercise

^eX² test