Skip to main content
. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Atherosclerosis. 2015 Sep 5;243(1):44–52. doi: 10.1016/j.atherosclerosis.2015.08.031

Table 2.

Risk of CHD (MI/ CHD deaths) (HR with 95 % CIs) per minor allele of AHSG genotypes and per 1 SD difference in genetically predicted fetuin-A in CHS cohort.

CHS cohort Caucasians African Americans
P P
Genotype n= 2,733 n= 566
rs2248690 1.12 (1.00– 1.26) 0.05 0.98 (0.74– 1.29) 0.87
rs4917 1.02 (0.91– 1.14) 0.73 0.88 (0.67–1.17) 0.39
Genetically predicted fetuin-A n= 2,733 n= 566
rs2248690 0.84 (0.70– 1.00) 0.05 1.06 (0.47– 2.42) 0.89
rs4917 0.97 (0.82– 1.14) 0.72 1.34 (0.72– 2.48) 0.36
Both variants 0.93 (0.79– 1.09) 0.35 1.26 (0.70– 2.28) 0.44

Association of AHSG genotypes and risk of CHD was assessed by ordinary Cox– regression and association of genetically predicted fetuin-A and risk of CHD was assessed by two-stage Cox-regression. All analyses were adjusted for age, sex, and clinic. Participants reporting previous CVD were excluded from the analyses.