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. Author manuscript; available in PMC: 2016 Nov 10.
Published in final edited form as: Int J Pharm. 2015 Sep 15;495(1):393–403. doi: 10.1016/j.ijpharm.2015.08.089

Figure 1.

Figure 1

DoE model obtained for dexamethasone loading prediction of microspheres prepared using polymer blends. Contour plots (A and B) indicating correlation between drug loading and two independent variables. A: DLG7E ratio in the polymer blend and total amount of PLGA (the total amount of dexamethasone was set at 85 mg). B: Dexamethasone amount added and total amount of PLGA (DLG7E ratio was set at 80%). C: Mathematical equation used to predict dexamethasone loading. D: predicted versus actual experimental values based on the model, the line indicates a linear fit.