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. Author manuscript; available in PMC: 2016 Nov 10.
Published in final edited form as: Int J Pharm. 2015 Sep 15;495(1):393–403. doi: 10.1016/j.ijpharm.2015.08.089

Figure 5.

Figure 5

Particle size and size distribution (volume based) for the star points of the CCD microspheres (n=3). Center point parameters were used for these formulations except: 1) the DLG7E ratio was different for CCD-1 (20%) and CCD-15 (100%); 2) the dexamethasone amount was different for CCD-3 (50 mg) and CCD-6 (100 mg); and 3) the total polymer amount was different for CCD-8 (400 mg) and CCD-17 (600 mg). The paired student's t-test was performed to determine whether there were any statistically significant differences. P<0.05 was considered as a significant difference.