TABLE 2.
In vitro antifungal susceptibilities of Yarrowia lipolytica isolates in this study
| Isolate | MIC (μg/ml)a for: |
Disk diffusion zone diameter (mm) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Azoles |
Echinocandins |
Others |
|||||||||
| FZ | IZ | VOR | PZ | CAS | MF | AND | AB | 5-FC | FZ | VOR | |
| PW3298 | 4 | 0.25 | 0.03 | 0.50 | 1 | 1 | 0.50 | 1 | 16 | 20 | 25 |
| PW3299 | 4 | 0.50 | 0.06 | 0.50 | 0.25 | 0.12 | 0.03 | 1 | 4 | 20 | 28 |
| PW3300 | 4 | 0.12 | 0.03 | 0.50 | 0.50 | 0.50 | 0.12 | 1 | 8 | 20 | 26 |
| PW3301 | 16 | 0.50 | 0.25 | 0.03 | 0.02 | 0.03 | 0.03 | 0.25 | 0.12 | 6 | 6 |
| PW3302 | 0.50 | 0.06 | 0.03 | 0.12 | 0.06 | 0.12 | 0.03 | 0.50 | 4 | 21 | 25 |
| PW3303 | 2 | 0.25 | 0.03 | 0.50 | 0.50 | 0.50 | 0.12 | 0.50 | 8 | 25 | 30 |
| PW3304 | 16 | 0.50 | 0.25 | 1 | 0.50 | 0.50 | 0.50 | 2 | 16 | 13 | 30 |
| PW3305 | >256 | 2 | 2 | 2 | 0.50 | 0.50 | 0.12 | 1 | 16 | 6 | 6 |
| PW3307 | 64 | 1 | 1 | 2 | 0.25 | 0.50 | 0.25 | 0.25 | 0.50 | 6 | 6 |
| PW3308 | 128 | >16 | 2 | >8 | 0.50 | 1 | 0.12 | 0.50 | 4 | 6 | 6 |
| PW3309 | 128 | >16 | 2 | >8 | 0.50 | 1 | 0.12 | 0.50 | 8 | 6 | 6 |
| PW3310 | 128 | >16 | 2 | >8 | 0.50 | 1 | 0.25 | 0.50 | 4 | 6 | 6 |
| PW3311 | 64 | 1 | 1 | 2 | 0.25 | 0.25 | 0.12 | 0.25 | 0.50 | 6 | 6 |
| PW3312 | 64 | 1 | 1 | 2 | 0.12 | 0.25 | 0.12 | 0.25 | 0.50 | 6 | 6 |
| MIC data | |||||||||||
| MIC range | 0.50–>256 | 0.06–>16 | 0.03–2 | 0.03–>8 | 0.02–1 | 0.03–1 | 0.03–0.50 | 0.25–2 | 0.12–16 | ||
| MIC50 | 16 | 0.50 | 0.25 | 1 | 0.50 | 0.50 | 0.12 | 0.50 | 4 | ||
| MIC90 | 128 | >16 | 2 | >8 | 0.50 | 1 | 0.50 | 1 | 16 | ||
a
5-FC, flucytosine; AB, amphotericin B; AND, anidulafungin; CAS, caspofungin; FZ, fluconazole; IZ, itraconazole; MF, micafungin; PZ, posaconazole; VOR, voriconazole.