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Hdac3 is required for progression through the CD4/CD8 double-positive stages of thymocyte development. (A) FACS analysis of CD4/CD8-positive cells further fractionated by CD25, CD3, and TCRβ expression. (B) FACS analysis of CD4/CD8-positive cells further fractionated using CD5 or CD69 versus TCRβ expression. Plots are representative of those from analyses of at least 5 mice. Arrow, TCRβhi/CD69low population.
