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A TCRαβ transgene complements the Hdac3−/− defect in thymocyte development. (A) FACS analysis of CD4 versus CD8 cells in nontransgenic control mice (Non-Tg) and Hdac3−/− mice versus mice expressing the indicated transgenes. (B) The defect in CD5 expression in Hdac3−/− mice is largely corrected by the TCRαβ transgene. Plots are representative of those from analyses of at least 5 mice.
