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Constitutively active PGC1β (CA-PGC1β) does not rescue cell viability of HCT116 cells following depletion of K-Ras, KSR1, or AMPKγ1. (A) Immunoblot showing ERRα protein levels with either an empty vector control (V0) or CA-PGC1β. (B and C) Immunoblot showing K-Ras, KSR1, AMPKγ1, and PGC1β levels (B) corresponding to the viability data in control (V0) and CA-PGC1β-overexpressing cells (C). RLU, relative light units.
