Fig. 4.

An A₁ receptor antagonist blocks the effect of adenosine on synaptic inputs to interneurons. A: voltage-clamp recordings from an interneuron held at −60 mV revealing spontaneous synaptic inputs in control, with the A₁ adenosine receptor antagonist DPCPX, in DPCPX and adenosine, and wash. B: averaged data showing that there was no change in the amplitude of synaptic inputs in the presence of DPCPX and that DPCPX blocked the previously observed effects of adenosine (n = 10). C: averaged data showing that there was no change in the interval between synaptic inputs in the presence of DPCPX and that DPCPX blocked the previously observed effects of adenosine (n = 10).