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. 2015 Oct 19;6:236. doi: 10.3389/fphar.2015.00236

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Copyright © 2015 Zheng, Ji, Lu, Tong, Fan and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The body weights of mice treated with Fructus Meliae Toosendan (FMT) water extract. The results showed that there were no significant changes in body weight between vehicle control (1% sodium carboxymethyl cellulose, n = 8) and FMT water extract groups (240 g/kg, n = 16) by oral gavage for 3 days; (B) Histological analysis of the liver tissues of FMT water extract-treated mice. Hydropic degeneration of hepatocytes was detected in FMT water extract-treated mice. The scale bar is 50 μm.