Table 3.

Comparisons of CEST/APT and DTI parameters values in the globus pallidus for Parkinson’s disease (PD) patients and normal controls (mean ± 95% CI).

		Normal (n = 23)	PD (n = 23)	P values
CEST/APT	MTRasym(3.5 ppm)	0.68 ± 0.17	0.84 ± 0.12	0.125
	${\text{MTR}}_{\text{asym}}^{\text{total}}$	2.20 ± 0.29	2.48 ± 0.38	0.259
DTI	FA	0.25 ± 0.01	0.24 ± 0.02	0.122
	MD	0.70 ± 0.03	0.72 ± 0.03	0.227

MTR_asym(3.5 ppm) was quantified by % water signal intensity. ${\mathit{\text{MTR}}}_{\mathit{\text{asym}}}^{\mathit{\text{total}}}$ was defined as the integral of the MTR_asym spectrum in the range of 0–4 ppm. FA, fractional anisotropy; MD, mean diffusivity.