Table 5.

Estimated risk coefficients for patients treated in INT-0091 and INT-0154 (P9354) [excluding patients in AEWS0031] (N = 716).

Factor	Characteristic	Relative risk	95% confidence interval	p value compared reference	Global p value
Age yrs. (ref. ≤9)					0.0043
	10–17	1.27	0.93–1.72	0.130
	18+	1.97	1.33–2.93	0.001
Primary site (ref. nonpelvic)					0.0173
	Pelvic tumor	1.44	1.07–1.92	0.014
Treatment (ref. standard timing)					0.0019
	Non-I/E	1.56	1.19–2.05	0.001
Tumor size, cms (ref. <8)					0.0005
	9–12 cm	1.24	0.93–1.65	0.137
	>13 cm	2.00	1.43–2.79	0.000