Table 1.

Demographic and clinical characteristics of study participants.

		Non-transmitters (Non-TM)
Characteristics	Transmitters (TM) N=91	Non-TM included N=91	Non-TM eligible for sequencing N=363	All other Non-TM N=2297	p-value* TM vs Non-TM included	p-value® (3 Non-TM groups)
Median maternal age (IQR), yrs	25 (24-28)	25 (23-29)	25 (22-30)	26 (23-29)	0.76	0.89
Median parity (IQR)	3 (2-4)	3 (2-4)	3 (2-4)	3 (2-4)	0.10	0.49
PEPI study arm, n (%)					1.00	1.00
Control	28 (30.8)	28 (30.8)	112 (30.9)	717 (31.2)
Intervention	63 (69.2)	63 (69.2)	251 (69.1)	1580 (68.8)
Median baseline CD4 (IQR), cells/μL	301.0 (208.0-451.0)	427.0 (274.0-583.0)	391.0 (268.0-595.0)	401.5 (267.0-588.0)	0.001	0.91
Median baseline log10 VL (IQR), copies	4.6 (4.1-5.1)	4.0 (3.6-4.4)	4.0 (3.4-4.6)	4.0 (3.4-4.6)	<0.0001	0.70
Median time to resumption of sexual activity (IQR), mos	6.1 (5.9-9.0)	6.0 (5.9-9.0)	6.0 (5.9-9.0)	6.0 (5.9-9.0)	0.77	0.82
Median BF duration (IQR), mos	9.0 (8.9-17.9)	9.0 (8.8-9.4)	9.0 (8.9-10.0)	9.0 (8.9-11.9)	0.048	0.61
Superinfection, n (%)	5 (5.5)	5 (5.5)			1.00

Abbreviations: N: number of individuals; TM: transmitter; non-TM: non-transmitter; IQR: interquartile range; PEPI: Post-exposure Prophylaxis of Infants in Malawi trial; yrs: years; mos: months; BF: breastfeeding.

^*p-values were calculated using Fisher's exact test for categorical variables, Wilcoxon Rank Sum test for continuous variables.

^®p-values were calculated using Fisher's exact test for categorical variables, Kruskal-Wallis test for continuous variables.