Table 2.
Association between maternal superinfection (SI) and mother-to-child transmission of HIV via breastfeeding.
| Unadjusted |
Adjusted |
||||
|---|---|---|---|---|---|
| Factors | n/N | OR (95% CI) | p-value | OR (95% CI) | p-value |
| Superinfection | 1.00 | 0.30 | |||
| No (ref) | 172/182 | 1 | 1 | ||
| Yes | 10/182 | 1.66 (0.52-5.27) | 2.32 (0.47-11.47) | ||
| Maternal age | 0.44 | 0.53 | |||
| 17-24 yrs (ref) | 68/182 | 1 | 1 | ||
| ≥25 yrs | 114/182 | 1.32 (0.73-2.42) | 0.79 (0.37-1.66) | ||
| PEPI study arm | 1.00 | ||||
| Control (ref) | 56/182 | 1 | |||
| Intervention | 126/182 | 1.00 (0.51-1.97) | |||
| Baseline CD4 cell count | 0.002 | 0.11 | |||
| <250 cells/μl (ref) | 49/172 | 1 | 1 | ||
| ≥250 cells/μl | 123/172 | 0.33 (0.15-0.69) | 0.50 (0.22-1.16) | ||
| Baseline log10 VL | 0.001 | 0.004 | |||
| <4 log10 copies (ref) | 55/157 | 1 | 1 | ||
| ≥4 log10 copies | 102/157 | 3.44 (1.64-7.43) | 3.06 (1.44-6.54) | ||
Abbreviations: N: total number of individuals; n: number of individuals with given trait; OR: odds ratio; CI: confidence intervals; PEPI: Post-exposure Prophylaxis of Infants in Malawi trial; VL: viral load.