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. 2015 Aug 6;309(8):G648–G661. doi: 10.1152/ajpgi.00170.2015

Fig. 3.

Fig. 3.

Reduced body weight and weight gain in L-Fabp−/− mice fed a high-saturated fat (SF) diet. A: average body weight of mice fed high-SF diet. B: average weight gain of mice fed a high-SF diet. Weight gain is significantly reduced in both NJ and WU L-Fabp−/− lines vs. C57BL/6J starting at 2 wk, as shown by the arrow. *P < 0.05 vs. C57BL/6J mice. #P < 0.05 between WU and NJ L-Fabp−/− genotypes. n = 10 C57BL/6J, 15 NJ L-Fabp−/− mice, 11 WU L-Fabp−/− mice. NJ Fabp−/− mice for this experiment are F1; WU Fabp−/− mice (2014) are N8, F14-15. C and D: comparison of current (2014) and historical (2007) data in WU L-Fabp−/− and C57BL/6J mice fed high-SF diet (n = 11–13/genotype). C: *Significant differences in body weight between WU L-Fabp−/− and contemporaneous C57BL/6J cohorts. D: differences in weight gain are significant after 3 wk on SF diet. 2007 WU L-Fabp−/− mice for this experiment were N7, F12-14. Values are means ± SE.