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. 2015 Aug 6;309(8):G648–G661. doi: 10.1152/ajpgi.00170.2015

Fig. 7.

Fig. 7.

Reduced obesity and steatosis in WU L-Fabp−/− mice but not NJ L-Fabp−/− mice fed a high cocoa butter (CB) fat diet. A: body weight (left) and weight gain (right) of female mice fed CB diet for 12 wk. n = 6–10/genotype. B: body weight (left) and weight gain (right) of male mice fed CB diet for 12 wk. n = 6–11/genotype. C: comparison of current and historical data in WU L-Fabp−/− mice fed CB diet, showing both body weight (left) and weight gain (right). In 2007 study, differences in body weight of L-Fabp−/− and C57BL/6J mice (n = 14–15/genotype) were significant (P < 0.05) after 7 wk on the diet. In the present study, differences in body weight between the genotypes were significant after 3 wk. D: hepatic TG content, expressed as μg TG/mg protein, in female (left) and male (right) mice fed 20% CB diet (2014 samples). n = 4–6 samples/genotype. For 2014 CB studies, NJ L-Fabp−/− mice were F7; WU L-Fabp−/− mice were N9, F7. For 2007 CB samples, WU L-Fabp−/− mice were N8, F3-4. Values are means ± SE. *P < 0.05 vs. C57BL/6J. #P < 0.05 vs. NJ L-Fabp−/− mice.