Table 4.
Characterization of fasted C57BL/6J and L-Fabp−/−mice
| C57BL/6J | NJ L-Fabp−/− | WU L-Fabp−/− | |
|---|---|---|---|
| n | 5 | 8 | 5 |
| Final BW, g | 21.6 ± 0.8a | 25.1 ± 0.8b | 20.2 ± 0.4a |
| Liver, g | 0.9 ± 0.1a | 0.9 ± 0.04a | 0.7 ± 0.1a,b |
| Liver/body, % | 4.2 ± 0.2a | 3.6 ± 0.1b | 3.5 ± 0.3b |
| Fat, g | 0.12 ± 0.06a | 0.41 ± 0.05b | 0.10 ± 0.04a |
| Fat/body, % | 0.5 ± 0.3a | 1.6 ± 0.2b | 0.5 ± 0.2a |
| Hepatic lipid | |||
| TG, μg/mg | 286.6 ± 56.7a | 83.7 ± 14.2b | 95.8 ± 25.1b |
| Chol, μg/mg | 17.5 ± 1.1 | 17.2 ± 1.1 | 17.8 ± 1.3 |
| FFA, nmol/mg | 101.8 ± 7.9a | 44.1 ± 5.4b | 86.7 ± 5.7a |
| Serum | |||
| TG, mg/dl | 31.6 ± 6.4 | 29.2 ± 6.7 | 32.8 ± 7.8 |
| Chol, mg/dl | 51.2 ± 4.2 | 48.2 ± 6.0 | 55.7 ± 7.8 |
| FFA, mmol/l | 0.35 ± 0.05 | 0.32 ± 0.07 | 0.38 ± 0.06 |
| Glucose, mg/dl | 135 ± 14 | 137 ± 19 | 137 ± 20 |
| β-HBA, μmol/l | 650 ± 155a | 362 ± 100a | 339 ± 89a |
Values are means ± SE; n, no. of mice. NJ, New Jersey; WU, Washington University; FFA, free fatty acid; β-HBA, β-hydroxybutyric acid. a,bDifferent superscript letters indicate significant differences between genotypes: P < 0.05.