. 2015 Aug 6;309(8):G648–G661. doi: 10.1152/ajpgi.00170.2015

Table 6.

Characterization of mice fed 20% cocoa butter diet

	C57BL/6J	NJ L-Fabp^−/−	WU L-Fabp^−/−
Females
n	10	6	10
Final BW, g	25.3 ± 1.2^a	24.6 ± 1.1^a	21.2 ± 0.6^b
Weight gain, g	7.0 ± 1.0^a	6.1 ± 1.0^a	3.2 ± 0.3^b
Liver, g	1.1 ± 0.1	1.0 ± 0.03	0.9 ± 0.1
Liver/body, %	4.3 ± 0.2	4.0 ± 0.2	4.3 ± 0.2
Fat, g	0.8 ± 0.1^a	0.6 ± 0.1^a	0.3 ± 0.02^b
Fat/body, %	2.8 ± 0.4^a	2.4 ± 0.2^a	1.3 ± 0.1^b
Serum
TG, mg/dl	12.9 ± 2.9	18.5 ± 3.4	21.2 ± 5.4
Chol, mg/dl	69.4 ± 3.4	56.8 ± 4.7	56.5 ± 4.9
FFA, mmol/l	0.32 ± 0.05^a	0.64 ± 0.1^b	0.50 ± 0.06^a
Glucose, mg/dl	337 ± 27^a	241 ± 30^b	251 ± 29^a
Hepatic lipid
TG, μg/mg	302 ± 23^a	361 ± 28^a	152 ± 28^b
Chol, μg/mg	20.8 ± 1.7^a	18.4 ± 1.3^a	12.3 ± 3.5^b
FFA, nmol/mg	80 ± 7	67 ± 5	60 ± 4
Males
n	9	11	6
Final BW, g	32.9 ± 0.8^a	36.0 ± 1.0^b	32.8 ± 1.6^a
Weight gain, g	9.8 ± 0.6^a	12.5 ± 0.6^b	10.3 ± 1.5^a
Liver, g	1.2 ± 0.04	1.3 ± 0.1	1.3 ± 0.1
Liver/body, %	3.7 ± 0.1	3.5 ± 0.2	3.8 ± 0.1
Fat, g	1.4 ± 0.1	1.3 ± 0.1	1.5 ± 0.2
Fat/body, %	4.3 ± 0.2^a	3.8 ± 0.1^a,b	4.5 ± 0.4^a
Serum
TG, mg/dl	28.3 ± 2.9	23.2 ± 3.1	37.5 ± 6.5
Chol, mg/dl	106.8 ± 4.9	90.7 ± 9.5	105.7 ± 8.9
FFA, mmol/l	0.30 ± 0.3^a	0.49 ± 0.09^a,b	0.54 ± 0.06^b
Glucose, mg/dl	349 ± 12^a	239 ± 35^b	434 ± 41^a
Hepatic lipid
TG, μg/mg	272 ± 48^a	274 ± 50^a	131 ± 32^b
Chol, μg/mg	18.0 ± 1.3	19.2 ± 1.4	17.2 ± 0.8
FFA, nmol/mg	98 ± 8	87 ± 4	96 ± 4

Values are means ± SE; n, no. of mice. ^a,bDifferent superscript letters indicate significant differences between genotypes: P < 0.05. Hepatic lipid was assayed in 5–7 animals per genotype. Serum was assayed in 5–6 animals per genotype.